diff --git a/api/kubernetes/cli/nodes_limits.go b/api/kubernetes/cli/nodes_limits.go
index ad7e04e28..91aa0a4eb 100644
--- a/api/kubernetes/cli/nodes_limits.go
+++ b/api/kubernetes/cli/nodes_limits.go
@@ -24,7 +24,7 @@ func (kcl *KubeClient) GetNodesLimits() (portainer.K8sNodesLimits, error) {
 
 	for _, item := range nodes.Items {
 		cpu := item.Status.Allocatable.Cpu().MilliValue()
-		memory := item.Status.Allocatable.Memory().Value()
+		memory := item.Status.Allocatable.Memory().Value() // bytes
 
 		nodesLimits[item.ObjectMeta.Name] = &portainer.K8sNodeLimits{
 			CPU:    cpu,
@@ -57,7 +57,7 @@ func (client *KubeClient) GetMaxResourceLimits(skipNamespace string, overCommitE
 	memory := int64(0)
 	for _, node := range nodes.Items {
 		limits.CPU += node.Status.Allocatable.Cpu().MilliValue()
-		memory += node.Status.Allocatable.Memory().Value()
+		memory += node.Status.Allocatable.Memory().Value() // bytes
 	}
 	limits.Memory = memory / 1000000 // B to MB
 
diff --git a/app/kubernetes/views/applications/create/createApplication.html b/app/kubernetes/views/applications/create/createApplication.html
index 8c3ecd44d..63b41adbc 100644
--- a/app/kubernetes/views/applications/create/createApplication.html
+++ b/app/kubernetes/views/applications/create/createApplication.html
@@ -285,7 +285,7 @@
                     namespace-has-quota="ctrl.state.resourcePoolHasQuota"
                     max-memory-limit="ctrl.state.sliders.memory.max"
                     max-cpu-limit="ctrl.state.sliders.cpu.max"
-                    validation-data="{maxMemoryLimit: ctrl.state.sliders.memory.max, maxCpuLimit: ctrl.state.sliders.cpu.max, isEnvironmentAdmin: ctrl.isAdmin}"
+                    validation-data="{maxMemoryLimit: ctrl.state.sliders.memory.max, maxCpuLimit: ctrl.state.sliders.cpu.max, isEnvironmentAdmin: ctrl.isAdmin, nodeLimits: ctrl.nodesLimits.nodesLimits}"
                     resource-quota-capacity-exceeded="ctrl.resourceQuotaCapacityExceeded()"
                   ></resource-reservation-form-section>
 
diff --git a/app/react/kubernetes/applications/components/AppDeploymentTypeFormSection/deploymentTypeValidation.ts b/app/react/kubernetes/applications/components/AppDeploymentTypeFormSection/deploymentTypeValidation.ts
index beb342735..f7490580f 100644
--- a/app/react/kubernetes/applications/components/AppDeploymentTypeFormSection/deploymentTypeValidation.ts
+++ b/app/react/kubernetes/applications/components/AppDeploymentTypeFormSection/deploymentTypeValidation.ts
@@ -14,6 +14,12 @@ export function deploymentTypeValidation(
     .test(
       'exhaused',
       `This application would exceed available resources. Please review resource reservations or the instance count.`,
-      () => !validationData?.isQuotaExceeded
+      (value) => {
+        // ignore this validation if the user has selected Replicated, in this case, the isQuotaExceeded will below the instance count input
+        if (value === 'Replicated') {
+          return true;
+        }
+        return !validationData?.isQuotaExceeded;
+      }
     );
 }
diff --git a/app/react/kubernetes/applications/components/ReplicationFormSection/replicationValidation.ts b/app/react/kubernetes/applications/components/ReplicationFormSection/replicationValidation.ts
index 2a84e5d05..922b28e55 100644
--- a/app/react/kubernetes/applications/components/ReplicationFormSection/replicationValidation.ts
+++ b/app/react/kubernetes/applications/components/ReplicationFormSection/replicationValidation.ts
@@ -24,7 +24,13 @@ export function replicationValidation(
       .test(
         'overflow',
         'This application would exceed available resources. Please review resource reservations or the instance count.',
-        () => !resourceReservationsOverflow // must not have resource reservations overflow
+        (value) => {
+          // the user can't fix the error here with 1 replica. There are validation errors in the resource reservations section that are helpful in a case of resourceReservationsOverflow.
+          if (value === 1) {
+            return true;
+          }
+          return !resourceReservationsOverflow;
+        }
       )
       .test(
         'quota',
diff --git a/app/react/kubernetes/applications/components/ResourceReservationFormSection/resourceReservationValidation.ts b/app/react/kubernetes/applications/components/ResourceReservationFormSection/resourceReservationValidation.ts
index 9b2791768..d21971f48 100644
--- a/app/react/kubernetes/applications/components/ResourceReservationFormSection/resourceReservationValidation.ts
+++ b/app/react/kubernetes/applications/components/ResourceReservationFormSection/resourceReservationValidation.ts
@@ -1,11 +1,21 @@
-import { SchemaOf, number, object } from 'yup';
+import { SchemaOf, TestContext, number, object } from 'yup';
+
+import KubernetesResourceReservationHelper from '@/kubernetes/helpers/resourceReservationHelper';
 
 import { ResourceQuotaFormValues } from './types';
 
+type NodeLimit = {
+  CPU: number;
+  Memory: number;
+};
+
+type NodesLimits = Record<string, NodeLimit>;
+
 type ValidationData = {
   maxMemoryLimit: number;
   maxCpuLimit: number;
   isEnvironmentAdmin: boolean;
+  nodeLimits: NodesLimits;
 };
 
 export function resourceReservationValidation(
@@ -28,6 +38,23 @@ export function resourceReservationValidation(
         ({ value }) =>
           `Value must be between 0 and ${validationData?.maxMemoryLimit}MB now - the previous value of ${value} exceeds this`
       )
+      .test(
+        'hasSuitableNode',
+        `These reservations would exceed the resources currently available in the cluster.`,
+        // eslint-disable-next-line prefer-arrow-callback, func-names
+        function (value: number | undefined, context: TestContext) {
+          if (!validationData || value === undefined) {
+            // explicitely check for undefined, since 0 is a valid value
+            return true;
+          }
+          const { memoryLimit, cpuLimit } = context.parent;
+          return hasSuitableNode(
+            memoryLimit,
+            cpuLimit,
+            validationData.nodeLimits
+          );
+        }
+      )
       .required(),
     cpuLimit: number()
       .min(0)
@@ -45,6 +72,41 @@ export function resourceReservationValidation(
         ({ value }) =>
           `Value must be between 0 and ${validationData?.maxCpuLimit} now - the previous value of ${value} exceeds this`
       )
+      .test(
+        'hasSuitableNode',
+        `These reservations would exceed the resources currently available in the cluster.`,
+        // eslint-disable-next-line prefer-arrow-callback, func-names
+        function (value: number | undefined, context: TestContext) {
+          if (!validationData || value === undefined) {
+            // explicitely check for undefined, since 0 is a valid value
+            return true;
+          }
+          const { memoryLimit, cpuLimit } = context.parent;
+          return hasSuitableNode(
+            memoryLimit,
+            cpuLimit,
+            validationData.nodeLimits
+          );
+        }
+      )
       .required(),
   });
 }
+
+function hasSuitableNode(
+  memoryLimit: number,
+  cpuLimit: number,
+  nodeLimits: NodesLimits
+) {
+  // transform the nodelimits from bytes to MB
+  const limits = Object.values(nodeLimits).map((nodeLimit) => ({
+    ...nodeLimit,
+    Memory: KubernetesResourceReservationHelper.megaBytesValue(
+      nodeLimit.Memory
+    ),
+  }));
+  // make sure there's a node available with enough memory and cpu
+  return limits.some(
+    (nodeLimit) => nodeLimit.Memory >= memoryLimit && nodeLimit.CPU >= cpuLimit
+  );
+}